Ultisil® XB-CN-unique selectivity for polar compounds

Ultisil® XB-CN column can be used in either reversed or normal phase. Reversed phase CN column has special selectivity for polar compounds, and due to its low hydrophobicity, elution of hydrophobic molecules is fast. Furthermore, XB-CN column shows perfect peak shape for strong basic analytes (including quaternary ammonium salts). Polarity of XB-CN column is the strongest among all reversed columns. It is a good choice for compounds that are strongly retained on standard reversed columns. Normal phase CN column can replace SiO2 column. Equilibrium of normal phase column is fast, and the silica surface activity is better than that of silica column. To prolong column life time, alternation between reversed phase and normal phase uses should be avoided. While XB-CN column can be used in either reversed or normal phase, elution sequence is different in different separation mode Cetilistat

 

Features

  • Can be used in either reversed or normal phases.
  • Stable bonding chemistry and excellent surface coverage.
  • Low hydrophobicity, unique selectivity.

 

 

Ultisil® XB-CN

Structural Formula  
pH Range 1.5-9.0
Particle Size 3μm, 5μm, 10μm
Surface Area(m2/g) 320(120Å)
Carbon Loading(%) 7(120Å)
USP List L10
Endcapped Yes

 

 

 

Rifampicin Isoniazid and Pyrazinamide

 

Column: Ultisil® XB-CN, 4.6×250mm, 5μm
Mobile Phase: 0.01mol/L sodium heptanesulfonate
solution* / acetonitrile=54/46
* Dissolve 2.0225g of sodium heptanesulfonate
in 1000mL water, adjust pH 1.85 with H3PO4
Detector: 254nm
Flow rate: 0.6mL/min
Temperature: 30°C
Injection Volume: 20μL

 

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